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Monitor Intently (1)phenobarbital will minimize the level or result of fentanyl transmucosal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Coadministration of fentanyl with CYP3A4 inducers could lead to the lower in fentanyl plasma concentrations, insufficient efficacy or, possibly, enhancement of a with

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